You're correct that this is a challenging design. Here are some possible solutions. You seem open to replacing your furniture, so that is my first thought: --Replace both sofas with comfortable armchairs with tallish backs that can be floated in the middle of the room around a coffee table. This will greatly add flow around the room so that you're not blocking all the inconvenient doorways. Note how a dramatic light pendant centers the seating. With the height you have, a beautiful pendant would have an incredible effect in both lighting the room and bringing down the scale to a more comfortable height. You have warm, wood floors in a beautiful color. Have a wooden bookcase in the same finish built to the left of your fireplace that can accommodate your TV. Have it built to the height of your mantel. Alternatively, get a very wide console, not too deep, for the TV. The one you have is too small and doesn't link in any way to the finishes in the room. Get an oversized large square or round rug for the room in a pattern that picks up the warmth of your wood finishes and echoes whatever upholstery you eventually choose for your seating. All art work should be hung at eye level regardless of how high your ceilings are. That means the center of each piece should be around 57" from the floor to the center of the art. Pair your daughter's paintings side by side at eye level. Lower the art work over the mantel so it's about 6" from the mantel so they connect. If you love that piece, or your daughter's art, then choose your future furniture palette--upholstery, pillows, etc. from the art. (This chair is the same silvery blue as in your painting. The legs are in similar wood finish as your wood floors and trim. Four similar ones--or these--around a round coffee table would look wonderful and really function well in the room.

Gabriella, a history of your comments shows that you're mostly interested in promoting the replica MCM chairs and sideboards sold at a NYC furniture store. You wouldn't happen to work there or own the store, or be friends or partners (personally or professionally) with someone who is, would you? Also, there have been more than a dozen BBB complaints in the past three years about the store you've been recommending, which I would find problematic if I were looking to buy something there. If you're trying to do native advertising/produce placement, you have to be less clunky and obvious about it. For example, not suggesting MCM furniture when the OP states a preference for farmhouse style.

OK. Here is Rev. 2. Still some measurement issues but mainly fireplace position. I think the TV over the fireplace is best because the angle and space to right of fireplace is not very large without overlapping Bay Area. I removed the soiled piece of the sectional to make everything fit nicely. (Convenient). I guessed on size. But these are fairly standard so I think I am close. I used Beverly’s idea for a console and art above it on wall to left of office doorway. I don’t know why the wall with the fireplace pops out but doesn’t go to office door. Might be worth building that out so the TV can be placed over fireplace nicely. But if not, we can design wall to have possibly a mantel that runs across and around end. Just depends on styling desired.

As far as arranging furniture with the columns, I would tend to ignore them and group seating around the fireplace. You are always in good company with a more flexible 3-seat sofa and two upholstered armchairs (or swivels.) I think a sectional will just add another complication to the space. What is opposite the fireplace? Are there any floor outlets near the columns or actually in them? Is there any electrical wiring in the bulkhead above them? They might be interesting if lighted. You could also install some glass shelves between the two that are near the exterior wall. Lighted from the top, that would be a great display for something like colored blown glass. As for the lighting, you can find less expensive variations on those. Scaling them for your room size will also lower the price somewhat.