Thanks for the help, all... No, not mixing ammonia and bleach, which produces mustard gas. Always worth mentioning, in case anyone doesn't know. Ammonia is supposed to be the best choice for sweat stains, didn't work this time. How much do I sweat? Dunno, pretty hard to quantify. This is a Select Comfort [sleep number] bed with 'Outlast' top and pad. Outlast is a special fiber that is supposed to absorb excess body heat, release it when you start to cool. Love the bed, but I think my comforter was just too thick. Had this happen to a much lesser degree when I got my first memory foam mattress, and those sheets were a cotton sateen, too. Tried the Oxyclean, no luck. Not on any supplements just now, they got lost in the move, haven't re-developed the habit. But the cold pre-wash is a good idea, will remember it. I really think the color of the fabric is changed. It doesn't look like the old color is under there, with an overlay of staining. They've actually changed, gone from a nice golden tan with subtle pinstripe to orange. Current plan: bleach them, try to dye them a uniform color [Is this possible with a front load?]. Nothing to loose at this point: these are Select Comfort's store brand of sheet, can go for $350/set. Got them on closeout [thank heavens!] but still. Thanks again...

johnmari: I've bookmarked the link to the resin-free sheets in case DD does not improve. Hopefully it may help the OP as well. I am finding this thread so fascinating with all of the different ideas, solutions and options--much more helpful than a visit to the dermatologist and getting an Rx for meds! In my history of dealing with various allergies (mine were mostly rhinitis whereas DD is eczema) one thing stands out that my allergist said to me years ago. That is that we spend 1/3 of our time/day in our bed and bedroom and if we can just get one thing under control, it's the bed. That should be the easiest to control--since there are so many other aspects of our lives when we go out of the home, eat foods out, etc. that are almost impossible. He also gave an analogy to think of allergies as having a glass of water. When you fill it up, it overflows. One solution to that is to get a bigger glass and another is to fill with less water. The "bigger glass" is everything we can do to enhance/improve our immune system and tolerance for allergens in our environment. For me this was a combination of years of immuniotherapy or allergy shots and more recently accupuncture and as of today I no longer require meds or shots to control my symptoms. For DD I have not got a complete handle on this though we've been doing Vit-B, probiotics, Omega3's, accupunture and more recently homeopathy. The second part "fill with less water" is to reduce the allergens we are exposed to. The home is where we have the most control and of this, controlling the bed and bedroom can have a huge impact so that we have more reserves to deal with the outside world.

First, a suggestion for removing blood (your own): the most effective solvent - even for dried blood - is the saliva of the same person. Just spit on it and let it soak in and then rub after it softens up. it may take a few doses but it always works. (Saliva of the same person is best; then same blood type, then same species, but when you get down to cross-species, it's not as successful at least not in my attempts on cat or dog blood.) Hydrogen peroxide is good, but saliva is completely non-damaging and an excellent first step. Generally, I don't need anything else. I find that bleach is insidious - you successfully shift the stain, and all seems well, but actually you've damaged the fabric and a hole is just waiting to happen. Now, for the mends, here's what I would do: With closely matching thread sew a row of very small backstitches about 1/32 inch from the torn edge (or more if you've a lot of fraying) along the edges of the tears or holes. This stabilizes the edges. Then darn over the hole, either by hand or with a machine. When carefully done you'll have the visible equivalent of a bartack/buttonhole stitch over the hole. And the mend will seem very inconsequential after the case is ironed. You'll never feel feel it in use. These types of mends on cases are very common in my household because my cats often jump up on the bed and the down pillows seem a little unsteady to them so they extend their claws. If I don't catch it right away, then a little tear gets bigger in the wash. Molly~

Right up Mamas alley...Hot water, and I don't mean the dubbed down hot in most washers now days, get that temp up to around 135 degrees f...Tide with bleach powder and a beautiful long soak..you may need to repeat this, but it should work.if you can get that temp even higher all the better.