It would depend on the market. Is this an area for singles, couples, kids? If the area is mainly singles, then a larger bedroom might attract more potential buyers, when you do sell. I mean, everyone else will probably have the two small bedrooms. But if it's couples, kids, etc. then the two bedrooms will be a better choice. Any chance you can make the smaller bedroom a den with double doors, if you decide on that option?

Obvs it depends on your needs! Maybe you could do a combination of both? - move bed into corner == two walls for windows - room for an office area - having the closet and bath in the same area == someone can get ready without traversing back & forth through the bedroom (and possibly waking the other person) - lots of room for a reach in closet opposite the walk-in closet (linen storage; shoes; out of season stuff; etc) - I might remove the shelves from the bathroom - your WC is a bit tight (where do you stand once you're inside & want to close the door??) If you remove the shelves you can push out the length of the WC

This is possibly (probably) more than you want to do, but it gives you two baths (one shared, one master) with a smaller addition, which might save enough on materials to change some of the interior walls. You'd have a bigger sitting area just inside the front door, with some flex space between it and the kitchen. The TV is drawn on an adjustable arm, mounted beside the front door, but could be on a small stand in the same location. The extra kitchen chair is beside the wall of book cases. I used your template for a couch, but there is space for a longer couch to convert to an extra bed. The kitchen table can be moved out from the wall when needed, and pushed out of the way when there is activity in the kitchen. The red lines denote the master bedroom and bath, and the green lines on the original plan, at bottom left, indicate interior walls which would not change (other than relocating a closet door from front to back). I changed the orientation of the tub and toilet in the second bathroom, to block the view of the toilet, but that wouldn't be necessary, and would be another saving in costs. The vanity in the master could become a single, with the toilet on the same wall. It's a small bath, with adjoining small closet, sufficient for AirBnB or student rental, but the bath could be enlarged, with a number of layouts, and one of the bedroom's exterior walls could be closet space (inset, bottom right). Moving the wall back into the first bedroom, and adding book cases or a combination of open and closed storage cabinets on the exterior wall, opens that long hall way into an extension of living space, and puts the entrance more in the middle of the room. No windows or exterior doors change. The area at the bottom of the smaller master bedroom could become a private porch or deck for the master. (Waving to any Smaller Homes peeps from the old days. :)

All the plans have a trade-off in room shape, cost etc. I agree that putting the bathroom in bedroom #4, the room width is the trade off. The bedroom width is currently 10'10". If I look at the adjacent master bathroom toilet cubicle, it's not much wider than the closet in bedroom #4. So the closet is probably 24" and the master bathroom cubicle 30". If the OP is OK with a 30" width then the middle plan may be the best one, since it only takes 6" off the width of the bedroom making it 13'10" x 10'4", and eliminating any door swing into the room.