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Fructose vs Glucose

John Liu
11 years ago

Many people have long named fructose sweeteners, especially high fructose corn syrup, as a contributor to obesity. Here is an interesting story.

http://www.bloomberg.com/news/2013-01-01/fructose-tied-to-obesity-as-study-shows-it-doesn-t-cut-appetite.html

Fructose, a sweetener found on many food labels, may contribute to weight gain and obesity because it has minimal effect on brain regions that control appetite, a study by Yale University researchers found.

The research, published yesterday in the Journal of the American Medical Association, is the first to compare the human brain's response to both fructose and glucose, two types of simple sugars used separately and together to sweeten food.

Researchers have long suspected that increased consumption of food flavored with fructose, a substance sweeter to the taste than glucose, may contribute to the U.S. obesity epidemic. The latest study used brain imaging to measure activity after the sweeteners were consumed. It found that only glucose had the ability to reduce blood flow in areas of the brain that regulate appetite, stopping people from wanting to eat more.

The data "surely suggest that it's probably not in your best interest to have high fructose-containing drinks because they're not going to cause you to be full, and you'll tend to consume more calories," said Robert Sherwin, a professor of medicine at Yale University School of Medicine in New Haven, Connecticut, in a telephone interview.

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