What are you wearing?
6 years ago
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What do you wear when you spray?
Comments (24)Insecticides and fungicides may be dangerous in different ways. That does not necessarly mean that one is less toxic than the other (in the long run). Some pesticide problems may not show up for many years and in a way unexpected such that that "route" was never tested for. The following recent research scientific paper is just one example of "the unexected/not tested". Title: Combined exposure to endocrine disrupting pesticides impairs parturition, causes pup mortality and affects sexual differentiation in rats Authors: P. R. Jacobsen, S. Christiansen, J. Boberg, C. Nellemann and U. Hass Authors affiliation: Department of Toxicology and Risk Assessment, National Food Institute, Technical University of Denmark, Søborg, Denmark Published in: International Journal of Andrology, volume 33, pages 434��"442, (2010). ABSTRACT: "Risk assessment is currently based on the no observed adverse effect levels (NOAELs) for single compounds. Humans are exposed to a mixture of chemicals and recent studies in our laboratory have shown that combined exposure to endocrine disrupters can cause adverse effects on male sexual development, even though the doses of the single compounds are below their individual NOAELs for anti-androgenic effects. Consequently, we have initiated a large project where the purpose is to study mixture effects of endocrine disrupting pesticides at low doses. In the initial range-finding mixture studies, rats were gavaged during gestation and lactation with five doses of a mixture of the fungicides procymidone, mancozeb, epoxyconazole, tebuconazole and prochloraz. The mixture ratio was chosen according to the doses of each individual pesticide that produced no observable effects on pregnancy length and pup survival in our laboratory and the dose levels used ranged from 25 to 100% of this mixture. All dose levels caused increased gestation length and dose levels above 25% caused impaired parturition leading to markedly decreased number of live born offspring and high pup perinatal mortality. The sexual differentiation of the pups was affected at 25% and higher as anogenital distance was affected in both male and female offspring at birth and the male offspring exhibited malformations of the genital tubercle, increased nipple retention, and decreased prostate and epididymis weights at pup day 13. The results show that doses of endocrine disrupting pesticides, which appear to induce no effects on gestation length, parturition and pup mortality when judged on their own, induced marked adverse effects on these endpoints in concert with other pesticides. In addition, the sexual differentiation of the offspring was affected. This as well as the predictability of the combination effects based on dose-additivity modelling will be studied further in a large dose-response study." -------------------------------------------- The first part of the INTRODUCTION SECTION of the full paper may be of interest: "Animal laboratory experiments have shown that in utero exposure to endocrine disrupting chemicals (EDCs) including some pesticides can cause adverse effects on male reproductive development (Foster, 2006; Gray et al., 2006; Hass et al., 2007; Metzdorff et al., 2007; Christiansen et al., 2008). Individual pesticides alone have so far not been shown to contribute to adverse human effects at relevant exposure levels. However, some studies indicate increased prevalence of cryptorchidism and decreased penile length in sons of women working as gardeners or Many EDCs have been found as mixtures in humans (Blount et al., 2000; Swan et al., 2005), including children (Brock et al., 2002; Swan et al., 2005; Main et al., 2006). Damgaard et al. (2006) observed an association between congenital cryptorchidism and the levels of certain organochlorine pesticides in mothers’ milk (Damgaard et al., 2006). Earlier, Pierik et al. (2004) identified paternal exposures to pesticides and smoking as factors associated with these congenital malformations. These initial observations in epidemiological studies points in the same direction as laboratory experiments with oestrogenic or anti-androgenic chemicals in which substantial mixture effects occurred even though each individual chemical was present at low, ineffective doses (Rajapakse et al., 2002; Silva et al., 2002; Hass et al., 2007; Metzdorff et al., 2007; Christiansen et al., 2008, 2009). Some pesticides such as vinclozolin and procymidone antagonize competitively the androgen receptor (AR) binding of androgens and affect mainly the reproductive development in male offspring (Kelce et al., 1997; Ostby et al., 1999). Other pesticides such as mancozeb and propineb act mainly via disruption of the thyroid hormones and are mainly suspected to disrupt brain development (Hurley, 1998; Hass & Axelstad, Personal Communication). Our detailed research on prochloraz, combined with studies on other azole fungicides such as tebuconazole and epoxyconazole, indicates that these pesticides have the ability to react through several endocrine disrupting mechanisms, and to induce various endocrine disrupting effects (Vinggaard et al., 2005a,b; Taxvig et al., 2007). We have shown that prochloraz induced anti-androgenic effects in rats in vivo in a Hershberger test as well as in a developmental toxicity study (Vinggaard et al., 2002, 2005a). In addition, our studies show that prochloraz increases gestation length and indicate that prochloraz may also affect thyroid hormone levels and cause effects on the sexually dimorphic development of the brain (Vinggaard et al., 2002, 2005a). Both tebuconazole and epoxyconazole increase gestation length and pup mortality and furthermore, these pesticides virilise female pups, and affect steroid hormone levels in foetuses and ⁄ or dams (Taxvig et al., 2007)."...See MoreWhat do you wear
Comments (56)ruth I am wearing the first ones I ever got which were from the Junior League Thrift Store, they are going on ten years old. I finally broke down and bought a new pair at JC Penny's last summer but I noticed the fabric is a bit thinner these days. The first pair are a little faded but are still like iron pants with no holes or snags and the stretch is still good, thats quality. After discovering how cool they keep you I've never worn anything else since in the garden, to tell the truth I live in spandex pants most of the time being totally spoiled by comfort. Speedo brand swimmers thongs or ones similar really have a good grip on the soles so they stay on your feet and never slip while walking because thats what they are made for, not slipping when wet. They also make handy bug swatters. Take it off, slap and its dead. Thank you catkin, we actually saw some sun this morning. I trimmed some stuff way back and then it started raining again but less than yesterday. I've gotten a lot of painting and patching I'd been putting off done indoors though, a work indoors weekend for sure....See MoreSunglasses -- what are you wearing?!
Comments (33)Thanks all.. I wish I could make cheap sunglasses work. Even sunglasses in a mid price range. Unfortunately, I need prescription lenses-- that with the $400 frames puts my sunglasses in the 1k range. I guess all the more reason to be sure I love them. What I really liked about the Stella sunglasses is the shape on my face and the way they fit. (I have a big nose but a narrow bridge and not all glasses sit well. These feel secure because they are held by the side of the nose.) I am less in love with the chain on the side but I do like the bit of bling and interest Walnutcreek, I think your Versace have a similar shape and I really like them. I may give them a try also. Lars-- I like your Versace glasses too! How fun are they? I think I will keep looking-- but I am definitely embracing the thought of sunglasses that make a bit more of a statement! Cropped most of my face out because it was a beast of a day and my skin and hair look terrible!...See MoreWhat do you wear when you garden?
Comments (31)I do dress for gardening because I have to go somewhere to do it (not just step out of the door) So I expect to have to put in some hours, either at the allotment or wood or at my few remaining customers) so yep, I have separate gardening clothes to non-work clothes...but not really any different, just grubbier. Tweed. Quite a lot of it. And stout leather shoes or boots. It will be a dark, dark day before I suffer either jeans or trainers UNDER ANY CIRCUMSTANCES. Or T-shirts for that matter. Or especially shorts. Just because it's a bit wet, cold or muddy, doesn't mean style has to go out of the window...and anyway, I find that wool hacking jackets and linen shirts(for summer) or my handknitted jumpers,(winter) improve with age and wear. I don't wear wellies or coats either (shapeless, horrible and cold). I don't really like wearing trousers but I do put up with leather ones for winter. I have several pairs of leather pants which I have worn for many years. Every winter, I am always somewhat cheered that another year has gone by without my bottom increasing in girth - although, tbf, leather, especially old, saddlesoaped and oiled leather, has a certain flex which is forgiving on my thunder-thighs. I always wear a hat (whether I am gardening or not) because I like them. Hats, that is. In summer, I tend to wear loose cotton frocks. And leather shoes. I never, ever garden in sandals., no matter how hot..and as for bare-feet...just no. I make a lot of my own clothes so I can use durable fabrics and include capacious pockets. I have a gardening neighbour at the allotment who has been wearing the same black and grey striped sweater for over 20 years....See More- 6 years agolast modified: 6 years ago
- 6 years ago
6 years agoI am in Albuquerque. It is cold, and white. I am wearing my fleece lined long pants, and an alpaca pull over.. just to be warm.
But this is my second outfit for the day. We went sledding this morning. Yep, sledding. Good thing, I didn't need to go anywhere in my own car.
amylou321 thanked OklaMoni
6 years agolast modified: 6 years ago- L.L. Bean rag wool slipper socks (with a hole in the right big toe!)
- Old J. Crew soft cotton lounge pants (a.k.a., pajama bottoms) in navy blue
- Comfort Colors pocket tee with logo from local haunt
- And topping it all off:
Keepin’ it classy! ;)Happy Thanksgiving!
amylou321 thanked Sammy- 6 years ago
- 6 years ago
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