The only thing I might look for would be toilet paper if I was a guest and discovered no toilet paper since everyone keeps spare rolls in the bathroom somewhere and under the sink would be logical.

I personally have never rummaged for toothpicks and if I need menstrual products for an emergency, I would ask the hostess directly as I have never stocked such things in the guest bath nor have I visited a private home in which such product were kept for guests. I don't think of my friend's guest bath as a place like a bathroom in a club where various toiletries are stocked and handed out by a worker :-)

I am not a rummager - don't look through medicine cabinets just because I can for example. Also I don't think I would want to use toothpicks stored under the bathroom sink :-)

Would I look under the sink for toilet paper? Yes. Toothpicks? No, nor would I make them readily available for guests because I don’t think toothpicks (the wooden kind) should be used to pick one’s teeth. I would be happy to provide (or ask the host for in a pinch) dental floss, though, since that’s usually used in front of a mirror and isn’t likely (hopefully) to make its way out of the bathroom like a toothpick would. :)

Unless they're looking for toilet paper- my guess is they'll tend to think it's off limits. I'd either tell them that under cabinet is stocked with some neccesary products (I usually show where the restrooms are right away. lol), or they'd ask me themselves.

If guests come to stay for longer time-I show them medicines stored in medicine cabinets in guest bath and powder room. Some usual stuff one might need. It'll have dental floss, additional toothbrush, etc.

that's a nice idea btw if applicable

I have four bins in our kids/guest bath. (the vanity is open with shelf in the middle though)

Three are dedicated, with a little nice sign(asked my DD to do that..cut out of nice paper and all, and attached with sort of a nice thread) with the name of whoever uses it, one has "Guests" written on it. when I'm not interested in seeing signs -when there are no guests-I just turn the bins the other way))

(if a guest arrives to stay for several days or weeks I write special sign with his name)

I tell them is their bin, thy can put there their stuff as not to take it back and forth, and I can put there things they might need.

so if you can find a way to mark the relevant drawer in a way that will fit your bathroom, and not read too..corporate-that's an option

Sounds like I will need to let people know. I do have counter space for a small sign. I guess that would be most convenient for a large party. For smaller gatherings, I’ll just tell guests to help themselves to whatever’s in the vanity when I show them to the powder room. Thanks everyone, for your help!