It's possible, but I wouldn't do it if it means the door to the bathroom would open into the kitchen.

How wide would the kitchen be? How wide are the aisles in your plan? It looks like a good, functional galley plan to me. You will want your aisles to be at least 48" wide to allow multiple workers. Some if us like them even wider. 54" seems to be my personal sweet spot.

For safety, the cooktop really should be moved down to the right of the sink, probably to the right side of the window. We spend more time prepping than we do washing so move your sink to the left of the window. Your prep space would then be in front of the window which is good. More window time! DW should be to left of sink, opening up into the wider area so people can walk around it.

ETA: I think your bathroom door placement is fine. It is in a short hall and turned such a way that a door accidentally left ajar won't have you seeing the toilet.

Funkycamper, I assume you're referring to the current bathroom location? The original question was about moving the bathroom to another location.

Yes, the second photo is the suggested plan and what my statement was referring to. Door down a small hall or niche, if you prefer, and toilet way back from door so one would not see it if the door was left open. Placement would be fine with me. YMMV

Could you post a floor plan of the whole floor this is on? It would be helpful to see what is around these rooms.

No one can reasonably answer that without much more information.

To determine if it is possible and how reasonable (expensive) requires knowing what is below, where the waste line exits the structure, how far to sewer/septic, and regional code. It looks like about a 20 ft move which is at the limits of a pump.

Get someone qualified to come in and look.

Here is the whole main floor plan:

The main part of the house is 2.5 stories, but the area I am working with is single story off the back of the house. The doorway with short stairs go to the basement landing and side door / back staircase.

The red cylinder represents the location of the main stack that bath ties into now, which was about 10 feet from the toilet. The current cast iron runs with minimal slope about 15 inches blow the joists, then drops another 32 inches prior to the tie in. The new toilet location in most of the layouts above is about 18 feet away, but should be able to get a three feet drop over that span if we need to. The exiting sewer is below the basement and runs back out under the stove to the alley. I am in Nebraska here, and I do have a plumber who will be running the drain and venting for me. I just hadn't brought him back in yet. Thanks!

Money can make anything happen. Lots of money, to basically repipe the whole downstairs. Cost vs. Benefit? Not so much.

Now that I see the whole floorplan, that bathroom doesn't make sense to me. Who uses that bathroom for bathing? It looks like there is just the one bedroom on that floor. Is that bedroom regularly used or a guest bedroom? The bathroom oddly placed and very inconvenient. It's crazy to have to walk down a hall, then through the dining room and kitchen to bathe. It would make more sense to me to expand the current powder room to add bathing and eliminate the full bath entirely. Or move the full bathroom right next to the bedroom. Could it fit above the down-going flight of stairs? Or are those stairwells all open? I'm not totally understanding your floor plan.

Thanks, I had planned to put one up, but was having trouble getting my program to export anything with the grid. Here is a screen shot, not sure if this helps enough.

The house is a 1910 four square that was converted to apartments in the 1940's. We live on the main floor and rent out two apartments upstairs. The powder room was apparently added where the stairs originally went to the basement landing (it was probably an open staircase) There may have had a very small tub at one time under the angle for the stairs above, but has been replaced with a cabinet,

The front stairs really don't get used except when tenants move larger furniture in or out, but they are over the top of the basement stairs, so can't really be removed. The more narrow back stairway was added during the conversion for the tenants to enter.

We have lived with the tiny 5x6 bath for 16 years and just want a larger shower and some storage. Maybe we have just adapted, but the bathroom being remote doesn't work too bad for us as we have very different schedules, and don't wake the other when getting ready. The hot tub is also right outside the side door, so it is handy to rinse off without dripping through the house. The current bath is also due for updates to the drain and supply lines, so there is going to be some cost even if I stay in the current footprint. I will try to post a couple of the other plans with a grid as well. Thanks!

Jillius, everything is correct, except both sets of stairs go up. Next to the narrow stair (darker circle) is the side doorway, leading to the basement landing (the lighter circle). The basement stairway down is underneath the front stairway going up. From that landing there are four stairs up to the door into the kitchen.

Jeremy, I would absolutely not want to face the door to the bathroom as I enter the kitchen. However, having the bathroom door in an alcove after I'm already in the kitchen, or having it to the side as I walk between the kitchen and dining room would work for me.

Your floor plan is one of the most challenging I've seen on this forum -- can't wait to see what the pros recommend.

I'm with texasgal47. I have no ideas, but seeing the current space and proposed changes side by side might help. Good luck!