> Great followup on "Kurt" - except it doesn't address any of the relevant points I raised. The doc in question is a cardiologist, makes inaccurate statements about hormonal therapy, uses testimonials instead of hard evidence and promotes a form of home lab testing in which he apparently has a financial interest, and which sounds highly dubious as to accuracy of results ... You are welcome to look at a clinical experience backed up by lab results as mere 'testimonials' - I think that there is a demonstrated link between low T3/T4 and elevated cholesterol, and I think that in many people, correcting an iodine deficiency is enough to restore the T3 and TSH levels to normal.... which is why I posted a link to that. As to his financial interests in the products he advocates, I don't know and don't pretend to know. On the radio yesterday, there was a discussion about doctors who make hundreds of thousands of dollars referring their patients to imaging clinics they own ... that type of possible conflict of interest seems to be rather common, and the medical boards don't seem interested in taking any action to stop it. I would not be surprised if "Kurt" actually does believe that levels of hormones like T3 and vitamin D and testosterone can be important in the development of heart disease, and that the testing is an accurate, cost-effective way to identify whether or not there might be a problem with any of these. But you would have to ask him. >> It remains true that taking iodine supplements is not the way to treat Hashimoto's thyroiditis - and could even be harmful. We have already established that large amounts of iodine can have negative effects - there is no dispute there. Where we have not agreed is related to smaller doses - it is my position that iodine deficiency can make any form of hypothyroidism worse, and reasonable amounts of iodine may be useful for some with hypothyroidism. Nope, we don't know that coconut oil had any effect in this regard. Beyond the unreliability of testimonial evidence in general ... Look, Magoo, the literature review I linked to above is not 'testimonials' - it was put together from dozens of studies related to MCTs and coconut oil - it found these compounds can in fact increase metabolic rate ... the shorter chain compounds enter cells without need for transport, and they burn faster and hotter than other fats. That word 'testimonial' seems to hold magical import in your psyche - you apparently think that calling any argument you disagree with a 'testimonial' proves that it is untrue (even when it is not even a testimonial)! This has nothing to do with the unreliability of testimonies - it is about an individual patient adjusting their lifestyle to feel better - a big difference, but something you can't understand since it is all so abstract and by the book for you. You deny that the patient can be aware of their own condition, or do anything constructive about their...

I took excessive amounts of D. Fortunately my doctor caught it, but D is not a safe vitamin. A,D,K. Those need to be watched. D is not regulated. I had it in my vitamins, and I took 1,000 extra in a pill. My doctor said I did not know how much I was really taking because it is not regulated. Even a year after I stopped taking the D, and only had it with my Calcium and Centrum, my blood count for D was at a safe level, but quite high. The whole media is on a D kick now, and you never hear about taking too much. The sun will not give you too much regarless of how long you are out. It is the pill that could cause you problems. Our winter has been so bad, that I think I probably need more now, but won't take it without having my blood tested. The teacher across the hall from me has two special lights to help with her SAD. Have any of you used those lights? Must go, Sammy

Based upon what Prarie love wrote, at least some people do believe that hypothyroid-induced seizures are common. Being hypothyroid and having seizures are not necessarily related, though they certainly can be. Unfortunately being that most animals do not get regular annual (twice yearly for older pets) bloodwork when they are healthy, but most people will get bloodwork done when their pet has a seizure, it is often the case that low T4 is discovered right after an animal has a seizure. But the seizure itself can cause low T4, and once the animal's seizures are controlled the T4 returns to normal- or not if the animal is on phenobarbital. This is euthyroid sick syndrome- normally functioning thyroid that is temporarily suppressed due to another disease. Euthyroid sick syndrome can be caused by any disease, including a disease that causes seizures or the seizures themselves. It doesn't hurt to judiciously supplement thyroid hormone in an emergency while waiting for a full thyroid panel, which takes 1-2 weeks (having just gotten one for my dog) as long as you don't go overboard, as oversupplementing thyroid hormone can be cardiotoxic. But you are not really controlling the seizures, you are actually preventing further seizures. In other words, even if a dog's seizures are caused by hypothyroidism, giving thyroid hormone won't do anything to stop the current seizures (explaination follows). The full thyroid panel can sort out euthyroid sick syndrome from true hypothyroidism if it is done prior to starting phenobarb, usually. Some pets refuse to be classified, like my own dog. I did a LOT of reading on this lately because my pathologists were stumped when I asked how hypothyroidism, which causes decreased cellular activity, could possibly cause seziures, which are caused by increased cellular activity. I would have asked the neurologists, but they were in rounds and then left before I could catch them. But I did find the info myself, and it seems that hyperlipidemia (VERY high serum triglycerides and/or cholesterol) may lead to atherosclerosis and then ischemic encephalopathy (low oxygen to the brain) due to hemorrhage or thrombus, causing seizures or other CNS signs (called a stroke in people). There are many causes for hyperlipidemia, hypothyroidism is one. One study showed that dogs that had atherosclerosis were 51 times more likely to be hypothyroid than dogs who did not have artherosclerosis (they showed similar results for dogs with diabetes mellitus). Hyperlipidemia may also cause hypercoagulable syndrome where an animal throws clots, which can end up anywhere. Clinical signs are referrable to location of clot, so if a dog threw a clot into the brain, that would also cause ischemic encephalopathy and possible CNS signs or seizures. Of course, bloodwork would pick up hyperlipidemia (well, a complete panel would show both cholesterol and triglyceride levels; some in-house machines can't do this), so waiting for a thyroid panel just tells you why the hyperlipidemia is present. Because hyperlipidemia may have causes besides hypothyroidism, it is much more important to include cholesterol and triglycerides in a seizure work-up than to include thyroid testing. You can always go back for a cause of hyperlipidemia if needed. That said, you need to have a full thyroid panel done before a pet is placed on phenobarbital because that drug suppresses thyroid hormone in some animals. It does not always cause clinical disease and may not always need to be treated. Once on phenobarb, it is very difficult to impossible to sort out true hypothyroidism from phenobarb-induced thyroid suppression. Without clinical signs though, there doesn't seem to be a need for treatment. Atherosclerosis appears to be rare in dogs overall, but common in dogs with hypothyroidism and diabetes mellitus. The actual incidence is unknown because you need either MRI, CT, or a necropsy to diagnose it. Most people don't have access to MRI or CT for their pets either because of expense or because it isn't available. And most people refuse necropsy. The unfortunate part about atherosclerosis is that once it is in the brain, you can't get rid of it, even by treating the underlying cause. If you can get the animal to stop having seizures and if there isn't too much permanent damage and if you can treat the underlying cause, you may be able to prevent more seizures depending upon how much of the brain is affected by atherosclerosis. The damage is done, and you have to prevent further atherosclerosis by treating the disease. In some cases, the damage to the brain may be too great and the patient dies despite best efforts, even if the cause was "just" hypothyroidism. Controlling hypothyroidism would also prevent further seizures due to hypercoagulable states caused by hyperlipidemia, but the same "ifs" apply. This is why supplementing thyroid hormone when presented with a seizuring animal isn't really necessary, even if the seizures are caused by hypothyroidism. You do need to control the hypothyroidism, but that can wait until the animal stops seizing and you have at least a clue of whether or not the animal is actually hypothyroid. It appears that the reason hypothyroidism is a rare cause of seizures in dogs is that most cases of hypothyroidism are diagnosed and treated long before a patient develops clincally significant hyperlipidemia and subsequent atherosclerosis. It seems that mild hypothyroidism without clinical signs does not cause the a high degree of hyperlipidemia, so the risk of seizures in this case is very small. I guess if you ignore the clinical signs long enough and don't do screening bloodwork on a regular basis, a dog could have severe hypothyroidism and seizures. BTW, collies are prone to hyperlipidemia without hypothyroidism, so in the case of poor Shelby, testing cholesterol and triglycerides is much more important than thyroid testing. You have to know what is common in certain breeds and ages, otherwise you end up running every test in the book and that is a waste of time, money, and effort.

No, I've never worked shift work and I'm not at all familiar with the studies you link. I was diagnosed with Graves in 1992, Hashimoto's about 10 years later, pretty much on the 'schedule' my endo had told me to expect. We treated Graves conservatively, PTU orally and it went into remission over time, now years later I take levothyroxine daily. Truthfully, I wasn't particularly ill with either disease, it was more like I was functioning but with a lot of little health annoyances :) - of course with annual screening, the Hashimoto's was detected and given attention early. I didn't have time to become too symptomatic, my doctor caught the change right away.