You might need to allow a little bit of flex with a filler if both ends of the cabinet run have side walls. I also like the left, but not the right.

Maybe go with the 39" base cabinets instead of 40" but cut the small pullout. I would put a pair of 36" cabinets over with a small upper filler to balance or step down to a pair of 33" or even 30" and add a wine bottle holder or some such thing on the end away from the range.

Do you have the option of finished ends on the wall cabinets beside the hood? If not, you may need to reserve a little for a finished panel on each side.

I’m guessing that the original plan had uppers that were all the same width - 20 inches each? If so, that’s perfect.
I do think a 40” wide drawer is too much.

They don't need to line up at all. The hood and the stove need to line up though. :P

I had 48" drawers in my previous house that held all my pots and pans and they worked fine for 17 years till we remodeled, even though the cabinet boxes and drawer glides were not of great quality. Go with a well built drawer and high quality heavy duty glides and you won't have any issues.

I just built and have 42" drawers on either side of the range. Drawer size is not an issue, but the quality of the drawer components is crucial.

I really dislike those utensil pull-out and don't think they hold much for the amount of space they occupy.

I also wouldn't worry about symmetry with the lower cabinets. Do you have an island? Can you even see the cabinets on either side of the range from across the room?

I would keep the 40" drawers on the right.

On the left just do a cabinet door, put one vertical divider inside and use the space to store cookie sheets, trays and large cutting boards.

Here are the rest of the kitchen plans for reference and it is completely open to the living room and visible from great room and fireplace.