All those doors in the den leave no room for furniture! I would not like looking at a toilet while in the kitchen. And anyone staying in that bedroom has to go through the kitchen to go to the bathroom. Not too crazy for the washer and dryer as is. naf naf already mentioned the tiny closet in the tiny room and huge hall....

Josh, Welcome to Gardenweb. Please read the link (New to Kitchens? Read Me First) which talks about the information that assists forum participants in helping with your kitchen design. Once you have read the thread, please post your proposed layout and the answers to the questions.

I couldn't find a way to distribute air with transfer beams in the second floor, 8-0 ceilings at the lower level and cathedral ceilings at the upper level. You may need floor trusses with the Mech room in the southeast corner. Get framing and HVAC plans to be sure its all going to work. I designed a house in Cataumet last year with cathedral ceilings and it got so expensive to frame the owners gave up.

Oh, there is an overhang, so you are planning seating. Aisles with seating require more space, as Verbo pointed out. Seating aisle minimums: If there are NO counters/cabinets/appliances behind the seats and the aisle has minimal traffic: 44" If there are counters/cabinets/appliances behind the seats and there is some traffic on the aisle: 54" If there is a table behind the seats: 60" (this does not apply in your case) Two seats cannot share a corner Island & Peninsula seating minimums: 24" linear space per seat Counter-height seating: minimum overhang is 15" of clear leg/knee space Bar-height seating: minimum overhang is 12" of clear leg/knee space. (Note that the top surface should be 18"D if any eating is planned at the counter to accommodate a plate + glass without risking knocking the plate/glass off the counter.) The "clear leg/knee space" depth is after accounting for any cabinets & decorative doors/end panels on the backs of the cabinets.