When I was planning my new bathroom remodel to include my W/D, I really had some limitations. But I got it in there and love it. I got a Miele set because they are 24" deep and wide, or there abouts. I stacked mine and that might be an option, but I like side by side better myself. I incorporated a cabinet surround that included storage, open shelving, and a pull out ironing board. I love it. All very efficient for the most part. The stacking kit has a shelf that pulls out and is great for folding clothes. I use the vanity on the other side of the room to hold more folded clothes. I have a small valet rod that pulls out, mounted inside the middle cupboard and use it to hang a few shirts for ironing. If you go with a top loader and side by side installation go with a Speed Queen. SIMPLE to use for the girls and built like a tank, I hear. Over on the laundry forum they love their Speed Queens. Built like all machines used to be built. No nonsense cycles. No bells and whistles. If my 26 year old Maytag top loader that I have in the basement ever quits, I will replace it with a Speed Queen if I still need 2 washers. Another thing about washers on the second story. There could be a bouncy problem in the spin cycle. My Miele instructions said to place the set on a load bearing wall. You don't want the set in the middle of a joist span because it will act like a trampoline I hear. Front loaders have tremendous force when in the spin cycle something like 1100 or more RPM, whereas a top loader might be around 700 RPM. Don't quote those numbers please :) Outlets in my laundry cabinets allow me to store and use my iron above my ironing board pull out. I also have a false back to the cabinet, where I can pull apart all the shelving and have full access to the w/d shut off valves, electric plug ins, and the dryer venting for cleaning. Because my Miele dryer has side venting option, that is why I could fit it in a 24" depth space. Outlets in the medicine cabinet that I had made, and an outlet under my vanity to store my hair dryer for daily use. It is a little bit awkward, as the cord can hang up when I pull out the pullout that houses the dryer. They have systems that retract the cord I believe and might be tidier. I put LED strips in 2 cabinets with infrared on/off switches and I LOVE this feature. I have them in my vanity under the sink, and in my laundry cabinet. I also have a strip in my Medicine cabinet. On my go-to LED online source their infrared switches are expensive so I got them on sale for $16 each, still expensive but I knew I needed them for my plans. I ended up doing an extra LED install, with a plug in power, instead of hard wired by electrician, so I needed another switch. I did a search and there is an small auto LED light shop that sells the same switch for around $8.

Well...here's a rather different idea. It's based on: --small kids who grow to be adolescents; --empty nesters using the house when the kids have left; --attempting to sell the house when it's time to downsize Build two, separate, hall oriented bathrooms, each with a space with two lavatories, and another space with a WC and tub/shower. Don't forget a linen closet for each.

I agree with Cpartist"s layout and like moving the closet over as suggested by D M so that bedroom 3 has easier access to the bathroom. Do you have room to have the toilet face the tub and add a linen cabinet next to the toilet? How wide is the tub toilet area?

As in one of your options where you question the purpose of the 'powder room', it may not be the ideal solution but I think is worth considering. For 90% of the time when you have no guest, you could use the 'powder room' and the shower/vanity area as your ensuite. For the 10% when you have guests then the whole space becomes a J&J just like you have now. The advantage of this layout is that your guests have their own vanity and that they don't need to go to your master-ensuite unless they want to take a shower. This one is pretty much the same as above except that I switched the toilet and the vanity in the 'powder room' and changed your closet configuration to give you a larger vanity. The mirror closet is now part of your master closet but it can stay in the guest bedroom if you whish: I am not sure where you place your bed. Is it against the bathroom wall or the exterior wall? If it is against the bathroom wall, you could do the same in the guest bedroom with this layout.