I have never seen any wild grapes that bear fruit here in Iowa. It is a weed that just feeds Japanese Beetles and leaf galls. Some of the varieties developed by the Univ. of Mn. like St Pepin for white or Swenson's Red are good for this area. Here is a link that might be useful: St Pepin

We have a wicked infestation of wild violet. Monterey makes an organic herbicidal soap that kills what's above ground but they'll come back. Our next attempt to get the violets out of our beds will be to cover the area with heavy black plastic for a week or two. Then we will remove the plastic to till the area and manually rake out the foliage and roots. I expect we will need to till multiple times to clear out all the roots. After this process we will put in our perennials, mulch heavily, and be vigilant for violets poking up through the mulch. I really don't mind them in the yard...just not in my garden beds.

I have the same problem - maybe our neighbors are related? I cut the blasted vine when it comes over into my yard (or even approaches my yard), and the closer I can get to the ground when I cut it, the happier I am. It's rooted in her yard, and she doesn't seem to care, so there isn't a heck of a lot I can do. I do look for the seedlings whenever I'm out and about in the yard, as I certainly don't want a full-blown vine in my yard. Very frustrating, when your neighbor does nothing. The neighbor behind us has a thicket of pokeweed that is about 15 feet wide and over 6 feet tall: happy birds, unhappy me. Ah well.

Grapes, wild or not, need a lot of sunlight to produce a crop of fruit. If you want this vine growing where it is there is no reason to not allow it to grow since a weed is a plant you do not want growing where you do not want it to grow.