I recently installed Google Chrome. Could this be an issue with the MS Updates not installing?

Quite possible if you were attempting to update in Chrome. MS does not like you using the competition to get at their updates. Did you try updating in IE?

On the very rare occurences thatI have had failures using MS update I disabled my antivirus and ALL other system monitoring applications and was then successful. Perhaps?

The hardest part was remembering to enable the applications.

DA

While it's a good idea not to run windows with administrator rights while browsing the web because it just makes it easier for malware to secretly dowload and install, unfortunately, I believe running as a limited user will not permit some windows updates to install. So when you tried to install windows updates, was it as administrator or limited user? Below is a support page from Microsoft.

You also may want to make sure you are virus free. There are many online scans available that you can run without going through the bother of installing as evidenced by this article:

http://blogs.computerworld.com/battling_antivirus_programs

Also, you may want to run an online scan at secunia to see if you have all patches needed for installed applications:

http://secunia.com/vulnerability_scanning/online/

Here is a link that might be useful: Microsoft support page regarding updates not installing

that update is failing for many people, there is a discussion about the problem over on BBR. Personally I would just leave it alone for a while, I know they have just issued an update for that update to try to fix part of it.
There is a work around mentioned on BBR thread if you want to follow the discussion.
Microsoft Security Bulletin Summary for October 13, 2009
that is the original thread for all the updates that day and on down in the pages you find the issues being discussed.

I keep my windows computers at .net 1.1 and have not had a problem with any programs yet, if I ever install something that tells me I need a newer version I will consider it then. Are you running stuff that has required newer .net?

Raven, I'm not running other things that has required a newer .net that I know of.

I've never had problems installing the updates until til past week. I'm glad to hear it's not just me - I'll give it some time and try again next week.

Graylight, I am running Windows as Administrator, I didnt know to do it any other way.

Give yourself some time and try those updates again. They would not install for me the first time around. I just waited several days and then they installed with no problem at all. Who knows?

Shaun, I'm having trouble with one of the net framework updates too but KB953297, have XP SP2. After a half dozen failures to install over about 8 days, I used Microsoft online support and ran, submitted the diagnostic scan they offer.

We may not be having exactly the same problem, but the response I rec'd this morning was 'The issue can be caused by a damaged .NET Framework component'. Microsoft gave me a set of instructions/links that begin with downloading a Windows Installer Cleanup Utility, removing .NET Framework 1.1, reinstalling ,NET Framework 1.1 Redistributable Package and its updates.

I've got dialup so will be time consuming and I had too much else going on today to work on it...I may try over the weekend.

morz8, I followed their instructions to do the same thing last week and it worked. But now I've got more updates and they won't install again.

I'll try again next week. Thanks.