I have not grown any Petunias or Nicotina, or anything else in that area besides zinnias. I think it's some type of weed, but I've never seen it before. The closest thing I could find that resembles it is Bittercress. Here's another picture of a smaller outcropping. Thank you all for the suggestions

If it's not the native, I would get rid of it. If it is the native, it's not suitable for all gardens, a monster of a vine. IDK how to tell them apart but someone around here probably does, if that's possible from your pics. It probably can't cause any trouble in a pot, aside from dropping seeds, if that option is appealing.

Ken, not all shrub honeysuckles are weedy, invasive species. :-) I wouldn't be without Lonicera nitida or L. pileata in the garden - excellent and versatile broadleaved evergreen shrubs. Or my latest favorite, the groundcovering Lonicera crassifolia. But none of these are the plant in question........and I have no guesses beyond what has already been suggested ;-)

Check undersides of leaves for little white larvae that look like grains of rice and/or fluffy white cocoons. Or a sticky clear residue on tops of leaves. If so, it is most likely whitefly, which I am currently battling myself. I have a pachira money tree, a similar looking plant to yours, with very similar recent leaf damage. they are resistant to most pesticides so neem oil is one of the few “pesticides” that kill them. But you have to be diligent and thorough with your application-every 7 days, spraying all parts of plant, particularly undersides of leaves. I’ve knocked mine back some w/ 2 treatments already.