Prehung doors come with the frames and hinges as one piece. Generally have the holes drilled for the openers.

Slab doors are simply the door, no hinges/hardware location holes.

Installing prehung doors means you remove all of the old door and frame. You then locate the new door/frame unit in place, plumb and level the frame members, and attach to the wall studs using shims(for plumb) and nails/screws. This can be done with a level, hammer/nails or screws/power screwdriver(drill/etc.). You would need a flat pry bar and hammer/screwdriver to remove the old frame. A reciprocating saw makes that job faster by cutting the old fasteners.

Installing a slab means removing the old door, using it to cut the new slab to fit. cutting hinge mortises and opener holes, installing the hinges/hardware, and hanging the slab in the old frame.

Replacing a slab means the door is seldom plumb or square and there is a fair amount of difficulty involved in machining the mortises and cutting the opener holes. You need two different sizes of hole saws and hammer and chisel as minimum tools. Professional tools include hinge location jigs and routers for the mortises along with the hole saws.

Hinges in prehung doors are generally basic brass colored, so matching hinges to opener hardware would require new replacement hinges. I do not remember ever replacing hinges to match opener hardware.

There are lots of videos showing both processes on YouTube.