A lot of people mix their finishes, it just depends on if you like the way it looks.

I love your leopard print idea; I think you should fly with it. At the end of the day, it's a bunch of neutral colors (that tie in nicely with the yellow you're stuck with), so use it as your starting point. If it were me, I'd paint the vanity a very dark espresso brown (I think going cream or ivory might be too much contrast). I'd go a bit lighter but still dramatic -- say a milk chocolate -- on the walls. Then I'd pick a flooring out of that same palette; not knowing your budget, I don't know what material would work, but anything from hardwood to cork tiles, to ceramic or porcelain tile, to vinyl would be fine, as long as the color ties together with the others. For accessories, pick some jungle-inspired greens, like palm tree prints and embroidered hand towels. Also, an amber glass soap dish or dispenser, and/or amber glass shades on the lights, would look great. Makes me want attach my powder room now...

Just some thoughts: Powder rooms can be made "L" shaped so the toilet is not what you see when the door opens. You see the side of a small wall sink in the corner you turn before seeing the toilet. A laundry room in the front isn't necessarily a bad thing. You might consider more of a laundry closet than a laundry room. You might be able to create a "mudroom" that is a hallway between house and garage with the washer and dryer facing each other at one end of that mudroom. You might be able to create a "mudroom" that is actually a hallway with a closet on one side hiding the washer and dryer and the powder room on the other set out so as the door opens between toilet and sink, the open door hides the toilet until it the door is closed.

It is no longer available. We had and then had to rip it up after toilet leak under the flooring. Flooring was rotted