Your layout could work too. These are my calculations:
- Toilet area: 36 in. wide
- Wall beside toilet: 36 in. long
- Vanity: 48 x 21
- Space between wall and vanity is 26 in.
If you were to go with this layout, I would suggest you either:
- Narrow the toilet area and/or
- Shorten the wall and/or
- Shorten the vanity and/or
- Steal some space from the closet
This would give you a wider space between the wall and the vanity. If you do many of the things listed above, you could maybe enclose the toilet area and not have the view of it when you are in the tub.
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Bathroom layout
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