Probably. It should be pretty easy to detect whether there are cut edges to the tile around the base of the toilet. I'm guessing you'll be fine. Even a lazy person would have recognized that it takes a lot longer to tile around a toilet than it does to pull the toilet, tile the floor continuously, and put the toilet back.

You need a design professional and General Contractor to work with you for this project. They can look at the options and suggest the most holistic approach that works with your site specifics. Good luck!

Hi Claire, thanks for thinking about my layout issue, and thanks also for the feedback! Yes, I am using sketchup. What program did you use to draw on my jpg? I wouldn't necessarily mind turning that staircase if the benefits outweigh the drawbracks, but I'm not sure what I would do with the rest of the layout, and I would also have to turn the basement stairs (there is a half staircase from the garage to the basement directly underneath the stairs currently in the living room) and the headroom for the new stair orientation would have to come from an upstairs closet (there is a bedroom above most of the current living & dining rooms). Also, the length of the wall where you wrote "open" is only 3' 1" (from the beginning of the stairs to the dining room wall). Our upstairs hallway is 3' wide and it seems very narrow.

I'm a little confused as to what you are asking. To answer the title question - I would not change flooring in the same room. Skip the powder room if it is a budgetary issue and continue the same flooring in the open kitchen/living/foyer areas.