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Al

I agree it's almost certainly over-watering; and, it's common for the symptoms to appear first in the portion of the variegation that has the least amount of pigment. There are some tricks that employ simple science, and they will help you help you deal with the excess water retention until you can repot into a more appropriate medium. This should help. Also, this is particularly useful when your planting is small and manageable:

Newton's First Law of Motion

Under conventional container culture, it's a given that saturated/partially saturated media rob roots of the oxygen they need to function normally and efficiently. At best, soil saturation robs your plants of immense measure of potential in areas like growth, appearance, yields, ….. At worst, plants unable to cope with the strain of drought stress caused by saturated media will succumb to it. This isn't a 'scare tactic, it's a very simple and straightforward observation that will be difficult to disagree with a straight face.

Newton's First Law of Motion states that an object will remain either at rest, or in motion at a uniform rate and in a straight line unless acted upon by an external offsetting force. In this case, we will designate the 'object' as excess water in your potting medium. At risk of my being redundant, the 'law' can be seen as a simple statement about inertia, that objects will remain in motion and in a straight line unless a force acts to change the motion. To put the law to work for you/your plantings, you should water to beyond the point of total soil saturation - so the medium has been completely saturated and at least 15-20% of the water you have applied has exited the pot. Unless your soil is purposefully constructed to eliminate all/nearly all excess water, it's extremely probable, when the pot has stopped draining, there will be too much water in the potting medium for the plants' liking.

To eliminate this excess water: immediately after a thorough watering, hold the pot in one hand over the sink, lawn, or over-sleeping significant other and move it downward, then sharply reverse the direction to upward. You'll immediately note that a good measure of 'excess' water will “continue downward in a straight line” and exit the drain hole. The sharper the reversal of direction, the more water exits the drain hole. When you have repeated the exercise until water no longer exits the drain hole on the reversal of direction, you will have eliminated all excess water and your plants will regard you with a newfound sense of awe.

Al

Radhika,
Have you ruled out pests? I would guess thrips. Look for tiny black dots on three underside of the leaf. This is thrips damage on my Pearl & Jade. I see the differences (the edges on your damaged areas are less defined than on mine).

I've just recently embarked on a thrips war. Hope I'm not afflicted by the old "if all you've got is a hammer, then everything looks like a nail" syndrome.

Good luck!

Elena

Thanks Elena and Al! I looked up images of thrips and so far it doesn't look like that's what it is, fingers crossed. I'll get to repotting it as soon as possible, seeing as its summer right now! I wonder why the sellers' gardeners would put pothos in soil like that. I've been perplexed about it since day 1...