Don't select one of those decorative free standing cabinets. Select one that begins at the wall and extend the top to over the toilet with a banjo top

I haven't seen that in a powder room...hmm, wonder how much more expensive that might be.

You need to be cognizant of the measurement between toilet and vanity for code. If you go larger will you still be within code restrictions? The free standing vanity is a more updated look.

The 37" would still be in code; the homebuilder originally had a 41" vanity.

Latifolia, I was going to put a pile of rolled and towels instead of the reusable towel that would spread everyone's germs.

There are also very pretty navy options with soft brass handles...pretty but white may be the safer, classic look...

The wall are Sherwin Williams silver strand which is a gray-blue-green-blend...but, we could easily change the color if going with the navy vanity. Thank you for your advice!

Does the navy tie into anything else in your home? Do you have Navy through out? I think if it is one of your accent colors it would be nice but if not it wouldnt have any type of relationship to anything else in the home. Also ask your self would you get sick of it? Silver strand is a pretty color and can go with the right tone of navy. For a powder room I would consider a fantastic wallpaper!

What will be the spacing of each choice from the wall.

It seems that if you do not move the plumbing you may end up with a difficult space next to the vanity.

If the original plan was 41" then it went from the wall to the 15" from toilet center.

A 37" will leave 2" on either side of the vanity. The toilet side is no problem, but 2" from the wall will be impossible to clean and a total PITA. 31" may not be a lot better with 5" from the wall. This is probably why the curved style was selected when the 41" was replaced.

You will still have plenty of room with a 37" vanity if wall to wall is 6'

It’s a powder room. Unless its traditional style is woefully out of sync with the rest of your home’s decor just remove some of the dated fittings and decoration and find a spectacular wall paper. No need to replace your vanity with an off the shelf Home Depot version like everybody has. 😊. Just my two cents...

I can't find anywhere that the OP says the original vanity is 41". Even if it were, it doesn't mean it was to code. GN is making the assumption that the center of the toilet is no more than 20" from the wall. The OP needs to provide real measurements of the room for anything to be meaningful.

If you put a banjo top (why would you do that?), you will need to replace the toilet with a low profile one, or you won't be able to access the tank.

I find those banjo tops kinda strang looking, and they seem somhow more germy.

Like a germ gangplank from the toilet to your sink.

Just my humble, uneducated opinion 🤷🏻‍♀️

You are focusing on the width of the vanity. You have, according to your drawing, only 21 (1/2?) inches of depth available next to the door opening. Is that to the door opening? Or to the trim around it? Your current sink is 19” from front to back....for a reason. Double check the measurement of any vanity that you are looking at so that it doesn’t protrude too far into the room.

IMO disposable towels are perfect in a powder room I really do not want to dry my hands on a towel some one else used ever not just now. I think the banjo idea might work in a family bathroom but really how much stuff do you need on a PR counter.I would stay with the smaller vanity add some art to the walls or wallpaper. I put my fresh flowers on the back of the toilet and a saop pump on the counter thats it. A waste basket under the counter and the extra TP there too . that is all that is needed in a PR

As far as germy towels, just remove the vase and put a basket of disposable towels. Real towels, rolled up when clean, need a hamper after being used.

Let's say you have a cocktail party or barbecue for twenty people, and each one uses the powder room just once, you would need at least that many hand towels, and you'd need a big hamper. And now you need to touch all those dirty towels to wash them.

Do a search for powder rooms and you will see lots of really creative and wonderful spaces. As noted above, if your current vanity works with your decor, spend the money on wallpaper, lighting and new fixtures.

If you have a pile of rolled hand towels you must have a basket on the floor to receive the used ones. A stack of one-use paper “hand towels” will work just as well, but you still need a receptacle for used ones. If you have good hand sanitizer soap in an attractive pump dispenser, you can put a fresh towel every day or three times a day, and just have a small trash bin for used Kleenex.

The wall to the trim of the door is 21.5.” The vanity is 22” deep, so we will pull it away from the wall.

If the proposed vanity is 22” deep and the measurement from trim to wall is 21.5”, the edge of the vanity is going to stick out past the trim. Ouch! (that’s what you’ll hear when folks hit their hip on the corner of that vanity.) Keep looking if you don‘t like what’s currently there.

You need to look for a vanity set up that is less than 21.5” in surface depth to the wall.

Your vanity choice is too deep then. You may be better off getting a base cabinet painted in the color you want (or have it painted). Do a rectangular shaped sink, which will give you more flexibility with depth and you can find scrap marble or stone in that size counter top to have made for the top. Then use some swanky hardware choices.

Most cabinet lines have the 18” deep built in vanity that you need as a standard choice. When things are settled back down, Ho to a cabinet design center.

This is my understanding of the layout of the bathroom

Based on this understanding, a 31" will fit, but will leave an awkward 5 1/2 " space between the wall and the vanity. A 37" will also work, but the space would only be 2 1/2" - not awkward, but impossible to clean.

The original 41" would require the trim to be cut out for the vanity if a traditional 22" vanity were to be chosen and you would need to be careful that the drawers/cupboards have room to open around the trim work.

Another option would be to have the plumbing moved or to get a vanity without a top and have a spacer placed between the vanity and the wall.

regarding the counter extended over the toilet: How does one access the tank? #BoundToHappen

I would not extend the countertop over the toilet. It’s a nightmare when it’s time to do work on the tank. The navy is rather striking and could really up the look.