There are a few issue with this overall design besides just the microwave.

First, you shouldn't have the sink and stove across from one another. It makes working in the space very awkward. Have them a bit adjacent. Second, that pantry design is not great IMO. It's a glorified hallway that creates a traffic path right into your kitchen. It also means that the microwave placement, which is otherwise fine, could be in the way. Make sure your aisles are wide enough as well. It's hard to read but they look a bit tight.

I use the microwave while cooking/preparing meals and for warming up leftovers at bfast/lunch. Having it as pictured, between the range and fridge, would be a good spot for me.

Putting it next to the pantry door could create a potential traffic jam. I'd put it at the other end of the range counter in the left corner.

IMO it depends on how many people cook at one time a sink back to back with a range would make me crazy I would change the window on the left to patio doors and forget the door from the deck . A 10 x10 space for a DR is pretty small The fridge is where it needs to be for cooking and close enough to the great room for use. You need a wider walkway in front of the fridge . I am happy your range is on an outside wall . The sink seems to be in a good spot so just make sure the walkway there is also 48” that might change the size of the island and IMO a good trade off.

Nice layout, have you thought about windows on the wall with the range? Maybe one tall window on each side. You will have a lot of cabinet storage plus that pantry so losing half of each of those upper cabinets on either side of the range won't be a big deal.

You could do the wine fridge area on the left of that back range wall. Then slide everything else over and do microwave area next to fridge.

Also make sure there is at least 42" of walkway, if not more, on all sides of the island.

I like that you have a pathway right to the kitchen from your garage and you can drop non-perishables off in the pantry on your way in. Especially heavy items like drinks.
I agree that moving the microwave to the left side would be optimal.
I like the fridge location. I don’t care for the wine bottle storage. Would make this just cupboard storage or open shelf. It is not good for wine to be stored where there is so much heat and vibration, and you can never change the purpose of that space.
I have a sink and range across from one another. I prefer the symmetry but I do have an ample space between, 48”
I’m curious about your fireplace location? It is unique and wonder what the rationale is for its placement in the corner.

Why are there two entrances to the pantry? I'd close the one from the mudroom and use the wall for cabinets or shelving.

Could your pantry doors be pocket doors? That would keep them out of the way as they will likely stay open most of the time.

In the mud room where you have two small closets?? Get the piece of wall between the two out and use bypass doors... way too many doors in there.

I would also do a pocket door from the pantry to kitchen..

The FP is on the wall where the great room is for seating the other space is DR space so the FP is in the perfect spot.