What aspect is awkward? Everything fits, you don't have to look at the toilet when you enter, etc. Seems pretty normal, unless that's a weird doorway at the top of the drawing...

It all depends on the structure underneath. You can't just move stuff around willy-nilly. The drains (especially toilet) have to be accounted for, and much of that depends on the joists under the floor and the direction that the drains have to run.

You need a plumber, not the internet.

I have no issue with the first layout and since some things can’t be changed now the only thing I can see it to have a shower and and a longer vanity to really make a change . Choose good quality tile keep the choices simple not too many different tiles get a nice quality vanity and do some decor that makes the space feel like a 5 star hotel bathroom.

Perhaps the weird layout is meant for weird guests?

If not, Mark's scheme is such an improvement, that I'd have the changes made, especially if you plan to stay in the home for more than a couple of years.

"we didn’t move the door there because then that corner wouldn’t be useable due to the other door being on the other corner."

What???

Mark's changes are so much better! Everything about it is better: more efficient use of space; bigger, more functional vanity; toilet near the window.

This is the second bathroom you have posted with really wonky window locations. I know you said that they couldn't be moved or they would look weird from the outside (though one has to wonder if other window placements are also wonky from the inside).

In both cases, I would give a very, very hard look at changing the windows. Framing can be changed now - at a cost of course, but it can be done. Living with really poor bathroom design for the life of the house - that seems too high a price to pay.

You know...if you don't want help, then don't post.

The recommendations here, and in your other thread, are significant improvements. How long do you plan to live in this house? If it's over two years or so, then make the changes. They will improve your living during the time you are in the house and boost your resale when you decide to leave.

My recommendation would be to put the tub underneath the window (maybe freestanding), and allow for a longer double vanity to go right in front of the lavatory!