The first season premiered on October 3, 2004 and introduces the four central characters of the show: Susan Mayer, Lynette Scavo, Bree Van de Kamp and Gabrielle Solis, and their families and neighbors on Wisteria Lane. The main mystery of the season is the unexpected suicide of Mary Alice Young, and her husband and son's involvement in the events leading up to it. Bree fights to save her marriage, Lynette struggles to cope with her demanding children, Susan fights Edie Britt for new neighbor Mike Delfino's affection, and Gabrielle tries to prevent her husband Carlos from discovering that she is having an affair with their gardener, John Rowland. The end of the first season results in Rex dying while believing Bree has poisoned him, Carlos being informed of Gaby's affair by John himself before being sent to prison, a fired Tom allowing Lynette to take his place as the bread-winner of the household, and a cliffhanger which puts Mike in danger of being shot by his own son.

The second season premiered on September 25, 2005 and its central mystery is that of new neighbor Betty Applewhite, who moved onto Wisteria Lane in the middle of the night. Throughout the season, Bree tries to cope with being a widow, unknowingly begins dating the man who poisoned her husband, fights alcoholism, and is unable to prevent the gap between her and her son from growing to extremes. Susan’s love life gets even more complicated as her ex-husband gets engaged to Edie, who has been promoted to the role of fifth lead, Lynette goes back to her career in advertising and eventually becomes her husband’s boss, and Gabrielle decides to be faithful to her husband, and begins preparations to have a child. In the closing moment of the season finale, Mike is run over by Susan's dentist friend Orson, who will become Bree's husband in the next season.

The third season premiered on September 24, 2006. In the third season, Bree marries Orson Hodge, whose past and involvement with a recently discovered dead body becomes the main mystery for half of the season. Meanwhile, Lynette has to adjust to having another child around the house, as a previously unknown daughter of her husband arrives. The Scavos also experience tension as Tom, Lynette's husband, wants to start a pizzeria. Gabrielle goes through a rough divorce, but finally finds new love in Fairview’s new mayor. Edie sees her chance to make her move on Mike, who is suffering from amnesia, while Susan moves on to a handsome Englishman whose wife is in a coma. Edie’s family relations are explored throughout the season. A shooting at the local grocery store leaves two characters dead and changes everyone's lives forever.

The fourth season premiered on September 30, 2007,[27] and its main mystery revolves around new neighbor Katherine Mayfair and her family, who returns to Wisteria Lane after twelve years away. Her daughter remembers nothing about living on Wisteria Lane. Also, Lynette battles cancer; the newlywed ��" but unhappy ��" Gabrielle starts an affair with her ex-husband Carlos; Susan and Mike enjoy life as a married couple and learn that they are expecting a child; Bree fakes a pregnancy and plans to raise her teenage daughter's illegitimate child as her own; and Edie schemes to hold on to her new love, Carlos. A gay couple from Chicago ��" Lee (Kevin Rahm) and Bob (Tuc Watkins) ��" become residents of Wisteria Lane when they move into the house formerly occupied by Betty Applewhite (Alfre Woodard), and Gloria and Alma Hodge. A tornado threatens to destroy everything, and everyone, that the housewives hold dear. The season finale has Katherine's abusive cop ex-husband killing and getting killed, then in the closing minute the characters and their story have flashed forward by five years: Bree is a successful cookbook writer, her son works for her, Gabrielle has had children, Lynette's twins are old enough to drive cars, and Susan has a new lover played by Gale Harold��"but what happened to Mike?

The fifth season premiered on September 28, 2008, with the time period jumping 5 years after the previous season, with some flashbacks to events which happened between the two periods. The season mystery revolves around Edie Britt's new husband, Dave Williams, played by Neal McDonough. Dave is looking for revenge on someone on Wisteria Lane (later revealed to be Mike Delfino and then, in a shocking twist, Susan). Susan deals with being a single mother and having a new romance with Jackson (Gale Harold). Lynette and Tom learn that their son is having an affair with a married woman whose husband's nightclub burns down with all of Wisteria Lane's neighbors inside. Carlos and Gabrielle have to struggle with their two daughters, Juanita and Celia, as Carlos's sight returns. Bree and Orson are having marriage problems because she is so focused on her career, and Orson begins to steal from neighbors as a coping mechanism. As a result, Orson is in the street when Edie is racing away from her house after her discovery that Dave is a madman plotting to kill Mike and all those he loves; Edie swerves to avoid hitting him and crashes into an electrical pole, then exits the car, only to die of electrocution before she can tell anyone that Dave moved to Fairview in order to get revenge on the person who killed his wife and daughter. It is later when Susan reveals to Dave that it was she, not Mike, who was driving the car the night that a woman and child ran a Stop sign because the sign had fallen over on a dark stretch of road. Dave's revenge plans suddenly change as he says "Hi" to M.J., Mike and Susan's son. This season featured the show's 100th episode, revolving around Eli Scruggs (played by Beau Bridges) a handyman who had an important input in all of the ladies' lives. This episode featured flashbacks and returning characters, including Mary Alice Young, Martha Huber and Rex Van de Kamp. The episode was broadcast on ABC on Sunday, January 18, 2009.

This is from Wikopedia.Hope it helps.

Vickey

Well if I read before I just paste and copy. Paul is Mary Alice's husband. SHe committed suicide because their secret had been found out...Their son was really the child of Mike and a druggie...and the druggies body had just been found...dead many years. They had killed her (don't remember why). Why he wants to buy all the houses I have no idea.

Vickey

Remember Paul's creepy son? I can't remember what happened to him.

Now, is this a weird show or not??? But, I love it! I plan my Sunday evenings around being in front of the TV when it comes on.....