I started hrt vivelle dot .5 and prometrium for three weeks and felt no relief. Went to another ob and he put me on Premarin 1.25 and Provera. My question is, am I starting from scratch as far as the relief, or will the three weeks of the other type of hrt count for something?

I was taking .9 Premarin and medroxyprogesterone for 1 and 1/2 years and my doctor stopped the medroxyprogesterone for 10 weeks due to my weepiness. My hot flashes returned, so I was instructed to take the medroxyprogesterone again. Took for 10 days and now having a heavy period after not having had one for 3 years. Can anyone help?

I don't understand the question.

It is interesting to read this lengthy list of so-called adverse effects. No information is given as to how many women in a control goup also had these same adverse effects. I would venture to say, the incidence of many of them would be the same in the control group. The drug company is required to list every complaint presented by a test subject whether there is any correlation to the trial drug or not. Elaine 8. The truth is that women are not all the same. After hysterectomy, there is no way to predict which form of estrogen, and/or which combination of estrogen/progesterone/testosterone will most benefit an individual woman. Some experimentation has to take place if the the first prescription is not satisfactory. For many years the general medical belief was that estrogen alone was needed after hysterectomy because there was no endometrium to protect. When Premarin was first touted as the panacea for women's menopausal woes, many cases of endometrial cancer were found in the women taking Premarin. Since progesterone was not absorbed when taken orally, Provera was invented. It is a drug somewhat chemically similar to progesterone and did work to counter the endometrial cancer problem. So when women had a hysterectomy, it was thought they did not need anything but estrogen. Today, more is being learned about the effects of all the sex hormones on all the tissues of the body. Since some women after hysterectomy feel better with both estrogen and progesterone, some doctors are prescribing it initially. Prometrium is the first oral progesterone chemically identical to the progesterone our bodies make. It is called "micronized" progesterone because a patented process makes it able to be absorbed from the gut. I believe it is a completely different drug from Provera and other molecularly altered progestins and can not be compared to them, yet most research makes no distiction between real progesterone and the altered "pretend progesterones". Many naturopaths and other alternative medicine practitioners turned to otc natural progesterone creams because it was the only way to obtain the molecularly identical progesterone. Drug companies did not want to manufacture and market this cream because it was not patentable, therefore not profitable. Also many doctors are skeptical of the transdermal route. My own internist, who is pretty open minded for a medical doctor, had the audacity to say to me when I was having excruciating breast pain from transdermal estradiol patches, that perhaps I wasnt absorbing it well through the skin. I looked incredulously at him and asked, why was I having the breast effects if I was not absorbing it; he became embarrassed and said, oh, I see what you mean; well it's my experience that many people do not absorb drugs well through the skin. I believe he has a set belief about transdermal drugs and leaves no room for differences in this area, even though he is open minded about others.