I would go with nothing BUT leather for my 3 large dogs (approx 100 lbs each). I went with a tobacco colored "distressed" leather. The nail marks only ENHANCE the look -- it just makes it look better and better.

There is no way to get all that accumulated dog hair off a fabric sofa, and I don't have to worry about having to constantly shoo them off of it. It works fantastically. They usually lay on the love seat, or the heated tile beneath it, and I get the big sofa (same setting).