that's a huge room but your items and placement are doing no favors for you. do you really need those two dressers because it's screwing up the bed area. any idea what you like? have you looked at all of the bedrooms here on Houzz to get some ideas? what I would do is center the bed on that wall and get two nightstands. Like this. you have no patterns in your room. trade out your solid drapes for something like this if you like the blue/white theme. you have enough room for a bench at the foot of the bed too. move that other dresser out of the room. For the large nook area, get a 6' or longer dresser to place there. a longer dresser means you don't need those two white ones. I assume you have a decent walk in closet? If any wall needs an accent color, it's the wall behind your bed. A nice deep navy would look great. if painting isn't your thing, try something on the wall like they've done here matching nightstands, lamps, a bench or the two ottomans, a nice white comforter, matching rug,,,, That is the focal point when you enter the room. Make it look nice! instead of that chair sitting out in no mans land, you have enough room for a low back sofa and ottoman at the foot of your bed. much better looking and will eat up some of that ginormous space. bring in a natural wood dresser like this vintage walnut piece for the nook. it will lend some warmth to the area. They made them long back then, so you can find something that will fit that area. hang some art and a mirror on the wall behind it. check craigslist or vintage furniture stores to find something like this or, if you want a sitting area, put a small sofa and an end table for a little sitting/reading nook. do you watch tv? media console and a large tv that can swing outward is another option. The little vanity is fine, but hang some artwork on the wall next to it, or a potted plant or something! the room is void of any decoration. (and please replace the white chair w/the proper vanity stool. most of those had stools at the time. And they look really nice painted what's the blue chair facing? is there a tv or something? do you sit there? might be better if you moved that. honestly, you have so many options it's mind boggling.

Another thing I love this bed .. But it's way out of my budget ! https://www.horchow.com/Bernhardt-Campania-Tufted-Queen-Bed/cprod127350002/p.prod?ecid=HCCS__GooglePLA&utm_source=google_shopping&adpos=1o1&scid=scplpcsku92130002&sc_intid=csku92130002&gclid=Cj0KCQjw9JzoBRDjARIsAGcdIDUcgKwFTD0WOSxBl8TuJjQbkCA6W3l3RB-Xdz0p3euPxqowbw8BYVUaAtrHEALw_wcB&gclsrc=aw.ds

My bedroom furniture has a similar wood color with sherwin Williams silverplate 25% lighter and it looks wonderful together along with off white simple linens. I think you are on the right track with neutral colors.

It is too high to use as a bedside table. Bedside table should be about the height of the mattress. Put it where you have the floor lamp