Your "My page" information indicates your are in Iran. The World Federation of Rose Societies does not list anything In the Mid East so this advice is based on warm climate rose growing.. If your roses grow year round with no winter dormancy. pruning back during the slower growing times of the year will promote more and larger blooms. Because modern roses bloom best on new growth, pruning will promote that growth, especially as spring approaches. Pruning once a year blooming roses will remove the bloom so they should not be pruned until after they bloom. Not pruning can result in tall leggy plants with smaller blooms. Better to prune during cooler weather, short daylight, and slow bloom cycles. If that means removing the beautiful flowers, that's a decision you'll have to make. I'd prune now and enjoy more and better flowers later.

If they are small bands that you're trying to grow up then yes, disbudding will help them to root and grow quicker. If they are larger bare roots or potted roses I don't think it matters. I do think you should let one bloom to make sure you have the correct rose. Even very good nurseries can make a mistake now and then.

Do you have pear trees or those pink weeping cherries? Those are blooming here now, too. And other orchard trees like peaches and apricots. I usually just prune out the discolored canes from winter, back until the canes are nice and green. Then prune out any canes that will cross too closely to another one (unless it's a small plant that needs all the canes and leaves it can get). You can take some height off of most modern roses if you like (or leave them tall), but if the rose only blooms once a year wait until after it blooms to do that. Some of the good canes may not actually be a great green. I have some that get kind of purple in the winter. That's fine. And some old canes can look kind of dead when they are just woody, so look for live buds pushing leaves if it's a particularly woody rose bush. Then you do have to cut off canes that have bad, cankered spots in them. You have to cut those off below the cankered area. Those are usually pretty obvious, I think (or I don't worry about the small ones). I hate to have to cut off long canes for that, but if you have a big bad spot on any cane, the cane will have to come off sometime. The canker can spread/creep down and up the cane, so go on and take care of that before the rose wastes all kinds of energy on the cane. Sterilize your pruners between cuts when dealing with canker.

I think there is some bacteria that will help get rid of the chemical they will absorb it and others will eat them. The ameoba and parameciams and protozoa that we learned about in 9th grade. Eventually the microbes will ameliorate. I like that word ameliorate the soil. It's your garden. Put what you want there. Maybe if you take some good soil from a place that you know grows good plants and sprinkle it on top it will rain down the good microbes. Maybe some good Organic fertilizers at the plant nursery will be good to sprinkle and make the soil good again. Don't they have something called starter fertilizers? To get the good things going again? I think rain eventually takes it away and it dissapates in the air and water and water vapor and the microbes.